The most important person; big enchilada, boss: Vance seems to be the main squeeze(1896+)
One's sweetheart, lover, etc: which center on his main squeeze, a girl in his Shakespeare class(1980+)
Idioms and Phrases with main squeeze
main squeeze
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One's boss, the highest authority, an important person. For example, Who's the main squeeze in this company? This slangy term was first recorded in 1896, and the precise allusion is unclear.
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One's sweetheart, as in Nancy is his main squeeze. This slangy usage, first recorded in 1970, alludes to the “squeeze” of a hug.